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What was the difference in life expectancy for the three groups that completed the study?
In the control group, the women aged 40–79 had a life expectancy of 79.5 years. In the comparison group, the men had a life expectancy of 84.2 years.
What were the most significant differences?
Women in the study were significantly older at the start than women in the control group, but this difference gradually decreased. The difference was large enough to be significant in the overall analyses, and to be statistically significant for two of the variables that were measured.
When did life expectancy increase in the comparison group?
The highest life expectancy was observed in the women who took part in the study; however, the differences between these two groups were much smaller than that between the treatment and control groups. The difference in life expectancy increased almost linearly between 1970 and 1990 after the introduction of the new drug.
How long were the participants in the study living?
The sample size decreased dramatically when the study ended; therefore, there is some doubt as to whether the study had any effect on the average life expectancy of the whole population.
How did people in the study age at death?
The average age of death increased by a mean of 10 years from 30-year to 42-year intervals in the control group but decreased by 12 years from 42-year to 46-year intervals in the comparison group (P<0.01).
How is this study different to other studies?
The study was designed to compare the effect of the use of oral contraceptives (OC) on women's life expectancy from the time of initiation of OC use, using data that is available at the time when the women are enrolled in the study (1970 and 1990). There are no previous studies in this area and so the results of this study were not to be expected. As well, most women in this study were over 65 years old at the start of the study. This was to ensure that the cohort was representative of the whole female population. Moreover, given that a similar approach has been used by other groups, the study was designed to be consistent with that approach.
What studies was this conducted in?
This study was conducted in two cohorts. The first, from 1968 to 1968, was a follow
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